The Diagnostic Medicine Consortium has officially launched, bringing together the Association for Pathology Informatics and Project Santa Fe Foundation, with the aim of adding other like-minded collaborating medical diagnostic societies. The consortium is committed to maximizing and standardizing the predictive value of actionable information generated by the diagnostic sector, so as to promote the proactive delivery of health care for individuals and populations. The goal is to shift from traditional reactive confirmation of disease conditions to proactive identification of risk for disease onset, while promoting a comprehensive approach to longitudinal chronic disease management. The DMC will also address maximizing the use of diagnostic information during episodes of acute illnesses.